@article {104, title = {Prescription Trend of Topical Corticosteroids in Outpatient of Dermatology in a Tertiary Care Hospital in Tumakuru, Karnataka}, journal = {International Journal of Pharmacology and Clinical Sciences}, volume = {5}, year = {2016}, month = {September 2016}, pages = {77-82}, type = {Original Article}, chapter = {77}, abstract = {

Background: Skin diseases amounts for a large fraction of patients attending the outpatient of dermatology and topical corticosteroids (TCS) are being commonly prescribed, the data related to drug usage patterns of TCS in skin conditions are particularly lacking. Hence it is vital to study the drug prescribing patterns of TCS in skin diseases. Objective: To study the demographic details and drug prescription pattern of TCS in patients with skin diseases. Materials and Methods: A cross-sectional study conducted in the Dermatology Department, Sri Siddhartha Medical College, over a period of 2 months. The patients with skin diseases who were prescribed TCS were included. The data was collected by direct observation in a specially designed proforma containing relevant detail such as demography, skin conditions and drug used. The data were analyzed as counts and percentages. Result: Majority of the patients were under the age of less than 20 years (38\%) followed by those between the age of 21 years to 40 years (36\%). .Female patients (61\%) were more and majority were from rural areas (69\%). Clobetasol propionate (46\%), mometasone furoate (15\%) and betamethasone dipropionate (12\%) were the commonly prescribed TCS. Fixed dose combinations (FDC) of TCS were commonly with fusidic acid, gentamicin and salicylic acid. Average drug per prescription was 2.09. None of the prescriptions used generic names. Conclusion: Prescription pattern provides critical feedback to prescribing physician by focusing on rationalizing drug therapy. FDC of TCS with gentamicin, salicylic acid and fusidic acids are rational and approved by CDSCO.

}, keywords = {Dermatology, Prescribing pattern, Rational, Skin disease, Topical corticosteroids}, doi = {10.5530/ijpcs.5.3.3}, author = {Purushotham K and Eesha BR} } @article {188, title = {Rationality of Prophylactic Antibiotic use in Genitourinary Surgery in a Tertiary care Hospital}, journal = {International Journal of Pharmacology and Clinical Sciences}, volume = {1}, year = {2012}, month = {Dec 2012}, pages = {106-110}, type = {Short Communication}, chapter = {106}, abstract = {

Antimicrobial prophylaxis is the periprocedural systemic administration of an antibiotic, used to reduce the risk of postprocedural local and systemic infections. The present retrospective study was done in 100 patients who had undergone elective genitourinary surgery in a tertiary care hospital to investigate the rationality of prophylactic use of antibiotics in genitourinary surgery according to the American Urological Association recommendations 2011. All patients undergoing genitourinary surgery had received antibiotics. Injectable antibiotic was administered within 1 hr before surgery in 95\% cases and 1-2 hrs before surgery in 5\% cases. Preoperatively single antibiotic was used in 92\%, two in 7\% and three in 1\% cases whereas postoperatively single antibiotic was used in 91\%, two in 7\% and three in 2\% cases. Most commonly administered antibiotic group preoperatively as well as postoperatively was a second generation cephalosporin, cefuroxime along with a beta lactamase inhibitor, sulbactam (90\% cases) followed by the combination of cefuroxime and an aminoglycoside, amikacin (4\% preoperatively and 5\% cases postoperatively). The number and group of antibiotic used preoperatively and postoperatively were quite identical. The average duration of antibiotic use was 3-10 days. The prophylactic use of antimicrobials in genitourinary surgeries in this hospital was rational with respect to time of administration and choice of antibiotic group. However, the duration of antimicrobial use was highly irrational which must be controlled to prevent the emergence of resistance strains and decrease the adverse effects and cost of health care to the patient.

}, keywords = {Antimicrobial, Genitourinary, Prophylactic, Rational}, author = {Rakesh Kumar and Jagminer Kaur Bajaj and Sukhbir Singh and Megha Sood} }