03408nas a2200289 4500008004100000245011400041210006900155260001800224300001200242490000600254520255100260653001502811653001302826653001602839653000902855653001702864653002102881653002302902653001502925653001702940100002502957700002002982700001703002700002203019700001903041856005803060 2019 eng d00aCost Analysis of Clinical Compounding in Saudi Arabia: Autoimmune and Gastrointestinal Pediatric Formulations0 aCost Analysis of Clinical Compounding in Saudi Arabia Autoimmune cNovember 2019 as19-s230 v83 a

Objectives: To explore the cost analysis of selected autoimmune and gastrointestinal pediatric formulations in Riyadh city, Saudi Arabia. Methods: This is a retrospective cost analysis study of autoimmune and gastrointestinal pediatric formulations at a pediatrics and maternity hospital in Riyadh city, Saudi Arabia. The extemporaneous pharmacy section regularly receive prescriptions with specific formulation from physician. The expert pharmacist applies the international standard of clinical compounding for all pediatric formulation related issue over 8 hr per days for 5 days per a week. The pediatric formulations consisted selected autoimmune and gastrointestinal medications. The cost analysis includes variable expenses such as personal cost, material cost and supply cost and fixed costs includes direct cost, non-salary cost and overhead cost. All costs were derived from the Ministry of Health information database. All costs were considered based on US dollar currency. In this study, we analyzed the cost of autoimmune and gastrointestinal pediatric formulations through the use of Microsoft Excel software version 10. Results: The estimated average total standard cost of pediatric formulations per hour was (53.82 USD). The average estimated cost of hydrocortisone per preparation was (12.896 USD). The total annual cost of hydrocortisone was (1547.52 USD). The average estimated cost of prednisolone per preparation was (4.6 USD). The average estimated cost of allopurinol per preparation was (6.99 USD) and the average estimated cost of sildenafil per preparation was (25.05 USD). The average estimated cost of omeprazole per each one preparation was (24.07 USD) and the total annual cost of omeprazole was (7221 USD). The average estimated cost of ranitidine per preparation was (5.248 USD) and the total annual cost of ranitidine was (2760.45 USD). The average estimated cost of baclofen per preparation was (21.266 USD) and the total annual cost of baclofen was (7655.76 USD). Conclusion: Based on the cost analysis, the cost of selected pediatric autoimmune and gastrointestinal pediatric formulations were higher than the ready-made products manufactured by pharmaceutical companies. The pharmacist should select the cheapest one among them. The cost analysis of pediatric formulation can be used to cover health insurance and meet the updated pharmacy strategic plan and New Saudi Vision 2030 in the Kingdom of Saudi Arabia.

10aAutoimmune10aClinical10aCompounding10aCost10aFormulations10aGastrointestinal10aMinistry of Health10aPediatrics10aSaudi Arabia1 aAlomi, Yousef, Ahmed1 aAlhadab, Malika1 aLubbad, Mona1 aBahadig, Faiz, A.1 aNazal, Ebtesam uhttp://ijphs.org/article/2019/8/3s/105530ijpcs2019840