Objectives: To explore the role of Pharmacist in an epidemic, pandemic, and emergency public health with an emphasis on Coronavirus Disease (COVID-19). Methods: It is a new initiative services drove by national and international infection control, epidemic, pandemic, and medicine disaster guidelines. The projects formulated the latest project from pharmacy project guidelines, the international business model, and project management institution guidelines. Project management professionals steps write the initiative project. It consisted of several parts, including the initial phase, the planning phase, the execution phase, and the monitoring and controlling phase. Results: The Role of Pharmacists in the epidemic, pandemic, and emergency public health emphasizes COVID-19 with a defined vision, mission, and aims. The services had multiple benefits, including clinical and economical on patients, as illustrated in the review. The continuity of the project is assured by the risk management model description. Besides, the monitoring and controlling of the services as declared. The transition to operation project through the closing project stage is explored in the analysis. Conclusion: The Role of Pharmacists in the epidemic, pandemic, and emergency public health emphasizing COVID-19 is essential and beneficial. The Pharmacist might contribute to the infection control at the pharmacy and healthcare system, provide enough supply from medications, and be involved in public health education about epidemic or pandemic management; it is highly suggested to implement other counties in Saudi Arabia the world.