@article {189,
	title = {Case of Fosphenytoin Induced Acute Cerebellar Dysfunction and Pituitary Bleed Causing Central Diabetes Insipidus in a Case of AML M2 during Allogenic Hematopoietic Stem Cell Transplant},
	journal = {International Journal of Pharmacology and Clinical Sciences},
	volume = {1},
	year = {2012},
	month = {Dec 2012},
	pages = {111-114},
	type = {Case Report},
	chapter = {111},
	abstract = {<p class="rtejustify">Neuroprotectors such as phenytoin, fosphenytoin, clonazepam or levetiracetam are often used prior conditioning regimen to prevent seizures caused due to busulfan, during bone marrow transplant. Fosphenytoin and levetiracetam are used instead of phenytoin as they are readily soluble and do not need a vehicle such as polyethylene glycol or ethanol which increases risk of tissue and cardio toxicity. We report a case of acute toxicity in the form of cerebral bleed during intravenous administration of fosphenytoin and its subsequent management in patient undergoing busulfan treatment prior to allogenic transplant.</p>
},
	keywords = {Bone Marrow Transplantation, Busulfan, Conditioning Regimen, Fosphenytoin, Levetiracetam, Neuroprotector, Phenytoin},
	author = {Eriat Govind and Radheshyam Naik and Srinivas BJ and Intezar Mehdi}
}
