03129nas a2200289 4500008004100000245009400041210006900135260001800204300001100222490000600233520228700239653001502526653001302541653001602554653000902570653001702579653002302596653001502619653001702634100002502651700002002676700001802696700003002714700001702744700001902761856005902780 2019 eng d00aCost Analysis of Clinical Compounding in Saudi Arabia: Antibiotic Pediatrics Formulations0 aCost Analysis of Clinical Compounding in Saudi Arabia Antibiotic cNovember 2019 as7-s100 v83 a

Objectives: The aim of this study to explore the cost analysis of selected pediatrics antibiotics formularies in the Kingdom of Saudi Arabia. Methods: It is a retrospective cost analysis of pediatrics formulations at 300-beds pediatrics and maternity hospital in Riyadh city, Saudi Arabia. The pharmacy section received the specific formulation from physician then the expert pharmacist applied the international standard of clinical compounding through providing to healthcare staff over eight hours per days for five days per a week. The pediatrics formulations consisted of selected four antibiotics (Nitrofurantoin, Oseltamivir, Chloroquine and Clindamycin). The analysis of the cost included the variable expenses included personal cost, material and supply cost, Costs fixed including direct cost, non-salary cost and overhead cost. The cost was derived from the Ministry of Health information database. All cost used US dollar currency. The study analyzed the cost of anti-hypertension pediatrics formulations through the Microsoft Excel sheet version 10th. Results: The estimated average total standard cost of pediatrics formulations per hour was (53.82 USD). The average estimated cost of Nitrofurantoin per each preparation was (14.13 USD) which consisted of standard cost (0.31 USD) and the direct cost was (13.82 USD). The average estimated cost of Oseltamivir per each preparation was (16.95 USD) which consisted of standard cost (0.33 USD) and the direct cost was (16.62 USD). The average estimated cost of Chloroquine per each preparation was (6.645 USD) which consisted of standard cost (4.36 USD) and the direct cost was (6.645 USD). The average estimated cost of Clindamycin per each preparation was (14.478 USD) which consisted of standard cost (2.018 USD) and the direct cost was (12.46 USD). Conclusion: There are varieties in the cost analysis between selected pediatric formulation and manufactured ready-made products. The pharmacist should select the cheapest one among them. The cost analysis of pediatrics formulation was used for health insurance coverage and to meet the updated pharmacy strategic plan and Saudi vision 2030 in the Kingdom of Saudi Arabia.

10aAntibiotic10aClinical10aCompounding10aCost10aFormulations10aMinistry of Health10aPediatrics10aSaudi Arabia1 aAlomi, Yousef, Ahmed1 aAlhadab, Malika1 aBahadig, Faiz1 aHarbi, Mohammad, Jabir Al1 aLubbad, Mona1 aNazal, Ebtesam uhttps://ijphs.org/article/2019/8/3s/105530ijpcs2019837